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Leading NMR diagnostics company numares recently published data showing that its novel, multi-marker approach to assess kidney function allowed for a more precise estimation of glomerular filtration rate GFR by a simple serum test. Named GFR NMR , the test provided metabolic characterization of renal dysfunction, by evaluating a group of metabolites. This "metabolite constellation" was comprised of myo-inositol, dimethylsulfone, valine, and creatinine, independently from age and sex. The test holds the potential for an improved assessment of kidney function, and deeper insights into kidney pathophysiology. This press release features multimedia. Graphic: Business Wire. In this proof-of-concept study, published in the peer-reviewed journal Diagnostics 1 , numares showed that a combination of multiple renal biomarkers, all with pathophysiological relevance, may overcome the diagnostic limitations of existing methods used to estimate GFR.
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The equation of time describes the discrepancy between two kinds of solar time. The word equation is used in the medieval sense of "reconcile a difference". The two times that differ are the apparent solar time , which directly tracks the diurnal motion of the Sun , and mean solar time , which tracks a theoretical mean Sun with uniform motion. Apparent solar time can be obtained by measurement of the current position hour angle of the Sun, as indicated with limited accuracy by a sundial.